In silico models for thrombosis and thrombolysis

 

Objectives

 

1. Further development of patient-specific models of thrombosis and thrombolysis;

2. Obtaining in vivo and in vitro biological data related to thrombosis and thrombolysis;

3. Combining thrombosis and thrombolysis models into a sufficiently fast model that predicts i.a. time to recanalization, changes in clot properties (mechanical), and erosion of micro-emboli;

4. Validation of individual models and combined model.